145585-75-7Relevant academic research and scientific papers
Catalytic remote hydrohalogenation of internal alkenes
Chen, Pinhong,Jin, Jianbo,Li, Xiang,Liu, Guosheng
, (2022/02/07)
Primary alkyl halides have broad utility as fine chemicals in organic synthesis. The direct halogenation of alkenes is one of the most efficient approaches for the synthesis of these halides. Internal alkenes, in particular mixtures of isomers from refine
Isoindoles having cardiovascular activity
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, (2008/06/13)
Isoindole compounds of the formula (I) STR1 wherein R1 represents hydrogen; C1 -C6 alkyl; benzyl optionally substituted with halogen, hydroxy, C1 -C6 alkoxy, methylenedioxy; C2 -C8 aliphatic acyl; benzoyl optionally substituted with halogen, hydroxy, C1 -C6 alkoxy, C2 -C6 alkanoyl, C2 -C6 alkanoyloxy, C1 -C4 alkyl, trifluoromethyl, methylenedioxy; R2 -R3 are selected independently from hydrogen; halogen; C1 -C4 alkyl; trifluoromethyl; hydroxy; nitro; amino; mono or di C1 -C4 alkylamino; cyano; C1 -C6 alkoxy; C2 -C6 alkoxycarbonyl; Y is ethylene, or a straight or branched alkylene chain containing from 3 to 6 carbon atoms, and the salts thereof of pharmaceutically acceptable acids. The compounds possess antianginal activity and are used in the preparation of medicaments for antianginal therapy.
