145587-61-7

Upstream product

• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 
• 7352-28-5 N-(benzyloxycarbonyl)-L-valyl-L-threonine methyl ester 

Downstream Products

• 145587-62-8 (4S,5R)-2-((1S)-1-benzyloxycarbonylamino-2-methylpropyl)-5-methyl-4,5-dihydro-oxazole-4-carboxylic acid methyl ester 
• 220717-68-0 2-((S)-1-{[2-((S)-1-{[(4S,5R)-2-((S)-1-Benzyloxycarbonylamino-2-methyl-propyl)-5-methyl-4,5-dihydro-oxazole-4-carbonyl]-amino}-2-methyl-propyl)-oxazole-4-carbonyl]-amino}-2-methyl-propyl)-thiazole-4-carboxylic acid ethyl ester 
• 220717-73-7 (4S,5R)-2-((S)-1-{[2-((S)-1-{[2-((S)-1-Benzyloxycarbonylamino-2-methyl-propyl)-oxazole-4-carbonyl]-amino}-2-methyl-propyl)-thiazole-4-carbonyl]-amino}-2-methyl-propyl)-5-methyl-4,5-dihydro-oxazole-4-carboxylic acid methyl ester 
• 220717-55-5 4-<2-(1-benzyloxycarbonylamino-2-methylpropyl)>-5-methyl-trans-oxazoline carboxylic acid 
• 182866-73-5 2-((S)-1-Benzyloxycarbonylamino-2-methyl-propyl)-5-methyl-oxazole-4-carboxylic acid methyl ester 
• 145678-71-3 Cbz-Val-αThr-OMe 

Relevant academic research and scientific papers

An improved protocol for azole synthesis with PEG-supported Burgess reagent

A polyethyleneglycol-linked version of Burgess reagent was developed and applied toward the cyclodehydration of β-hydroxy amides and thioamides. The desired oxazolines and thiazolines were obtained in high yields and excellent purities. The major advantag

Synthesis of cyclopeptide alkaloids by cyclooligomerization of dipeptidyl oxazolines

Cyclodehydration of Cbz-valylthreonine methyl esters with Burgess reagent provides access to cis- and trans-oxazoline segments for cyclooligomerization reactions. The ratio of 12-, 18-, 24-, and larger-ring macrocycles obtained in this process is kinetica