145678-71-3

Upstream product

• 145587-61-7 (4S,5S)-2-((1S)-1-benzyloxycarbonylamino-2-methylpropyl)-5-methyl-4,5-dihydro-oxazole-4-carboxylic acid methyl ester 
• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 
• 7352-28-5 N-(benzyloxycarbonyl)-L-valyl-L-threonine methyl ester 

Downstream Products

• 145587-62-8 (4S,5R)-2-((1S)-1-benzyloxycarbonylamino-2-methylpropyl)-5-methyl-4,5-dihydro-oxazole-4-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of cyclopeptide alkaloids by cyclooligomerization of dipeptidyl oxazolines

Cyclodehydration of Cbz-valylthreonine methyl esters with Burgess reagent provides access to cis- and trans-oxazoline segments for cyclooligomerization reactions. The ratio of 12-, 18-, 24-, and larger-ring macrocycles obtained in this process is kinetica