145628-71-3Relevant articles and documents
Investigation of the products of interaction of cyclic diketones with nitrogen-containing 1,4-binucleophiles
Kolos,Yurchenko,Orlov,Shishkina,Shishkin
, p. 1550 - 1559 (2004)
The interaction of arylbis(5,5-dimethylcyclohexane-1,3-dion-2-yl)methanes with o-phenylenediamine and o-aminophenol leads to the preparation of 3,3-dimethyl-11-aryl-2,3,4,5,10,11-hexahydrobenzo[b,e]-1,4-diazepin-1-ones and 3,3,6,6-tetramethyl-9-aryl-10-(2
Design, preparation and characterization of Cu/GA/Fe3O4@SiO2 nanoparticles as a catalyst for the synthesis of benzodiazepines and imidazoles
Shaabani, Ahmad,Sepahvand, Heshmatollah,Hooshmand, Seyyed Emad,Borjian Boroujeni, Mahmoud
, p. 414 - 421 (2016)
The synthesis and characterization of an efficient and reusable nanocatalyst, Cu/GA/Fe3O4@SiO2, obtained by ultrasonic-assisted grafting of guanidineacetic acid on modified Fe3O4@SiO2 core-shell nanocomposite spheres and subsequent immobilization of Cu(II), are described. The catalyst was characterized by means of X-ray diffraction, scanning and transmission electron microscopies, energy-dispersive X-ray spectroscopy, elemental analysis, thermogravimetric analysis, Fourier transform infrared spectroscopy, vibrating sample magnetometry and inductively coupled plasma optical emission spectrometry. The prepared nanocatalyst facilitated an efficient and straightforward friendly procedure for the synthesis of benzodiazepines and imidazoles in ethanol and under solvent-free conditions, respectively. The nanocatalyst can be easily recovered using a magnet and reused several times without any significant loss of activity.
A nickel nanoparticle engineered CoFe2O4@GO-Kryptofix 22 composite: A green and retrievable catalytic system for the synthesis of 1,4-benzodiazepines in water
Mozafari, Roya,Ghadermazi, Mohammad
, p. 15052 - 15064 (2020)
A composite of Ni nanoparticles incorporated in Kryptofix 22 conjugated magnetic nano-graphene oxide, CoFe2O4@GO-K 22·Ni, was synthesized via the grafting of Kryptofix 22 moieties on the magnetic nano-graphene oxide surface, followed by reaction of the nanocomposite with nickel nitrate. The Kryptofix 22 host material unit cavities can stabilize the Ni nanoparticles effectively and prevent their aggregation and separation from the surface. Characterization of the catalysts by FT-IR, FE-SEM, TGA, ICP, EDX, XRD, VSM and BET aided understanding the catalyst structure and morphology. This catalyst was efficiently applied for the synthesis of 1,4-benzodiazepine derivatives. The main advantages of the method are mild reaction conditions, inexpensive catalyst, it is environmentally benign, has high to excellent yields and shorter reaction times. This organometallic catalyst can be easily separated from a reaction mixture and was successfully examined for six runs with a slight loss of catalytic activity.
A novel magnetic nanocatalyst Fe3O4@TiO2-H5IO6 for the green synthesis of 4-substituted-1,5-benzodiazepine derivatives
Ahmadzadeh, Fatemeh,Etemad, Jamileh,Farahi, Mahnaz,Karami, Bahador
, p. 456 - 465 (2021/08/21)
In this study, periodic acid-functionalized magnetic support (Fe3O4@TiO2-H5IO6) as a new, benign and recyclable nanocatalyst was prepared by anchoring / periodic acid onto TiO2-coated nano-Fe3O4. This catalyst was applied to achieve a high-efficiency, low-cost and eco-friendly approach for synthesizing 4-substituted-1,5-benzodiazepines with the multicomponent reactions of aromatic aldehydes, o-phenylenediamine, and dimedone. The / periodic acid group on Fe3O4@TiO2 possesses both Lewis and Br?nsted acidity, which is responsible for the high catalyst activity. The obtained results show that the catalyst performance has been acceptable in the presented research. / The catalyst could be recovered and reused up to six times without any notable decrease in its activity.
