145642-77-9Relevant academic research and scientific papers
Thiolysis of oxazolines: A new, selective method for the direct conversion of peptide oxazolines into thiazolines
Wipf, Peter,Miller, Chris P.,Venkatraman, Srikanth,Fritch, Paul C.
, p. 6395 - 6398 (1995)
A direct oxazoline→thiazoline conversion can be realized by thiolysis of oxazolines with H2S in methanol/triethylamine, followed by cyclodehydration with Burgess reagent. This protocol is high-yielding, chemoselective, and essentially free of r
AN INVESTIGATION OF THE MITSUNOBU REACTION IN THE PREPARATION OF PEPTIDE OXAZOLINES, THIAZOLINES, AND AZIRIDINES
Wipf, Peter,Miller, Chris P.
, p. 6267 - 6270 (2007/10/02)
The diisopropyl azodicarboxylate-triphenylphosphine mediated cyclization of serine and allo-threonine derivatives provides peptide oxazolines, whereas cyclization of threonine containing substrates leads to N-acyl aziridines.In the thiopeptide series, onl
