145653-24-3

Basic information

• Product Name: {(2S,3R)-3-[(S)-Cyclohexyl-(diphenyl-phosphinoyl)-methyl]-oxiranyl}-methanol
• Synonyms: {(2S,3R)-3-[(S)-Cyclohexyl-(diphenyl-phosphinoyl)-methyl]-oxiranyl}-methanol
• CAS NO: 145653-24-3
• Molecular Weight: 370.428
• Mol File: 145653-24-3.mol

Chemical Properties

• CAS DataBase Reference: {(2S,3R)-3-[(S)-Cyclohexyl-(diphenyl-phosphinoyl)-methyl]-oxiranyl}-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: {(2S,3R)-3-[(S)-Cyclohexyl-(diphenyl-phosphinoyl)-methyl]-oxiranyl}-methanol(145653-24-3)
• EPA Substance Registry System: {(2S,3R)-3-[(S)-Cyclohexyl-(diphenyl-phosphinoyl)-methyl]-oxiranyl}-methanol(145653-24-3)

Safety Data

• Hazardous Substances Data: 145653-24-3(Hazardous Substances Data)

Upstream product

• 145653-05-0 (E)-4-cyclohexyl-4-diphenylphosphinoylbut-2-en-1-ol 

Downstream Products

• 148314-39-0 (2R,3R)-3-[(S)-Cyclohexyl-(diphenyl-phosphinoyl)-methyl]-oxirane-2-carboxylic acid 

Relevant articles and documents

Stereocontrolled Synthesis of R or S, E or Z Unsaturated α-Amino Acids by Enantio- and Diastereoselective Epoxidation of δ-Hydroxy Allylic Phosphine Oxides

Epoxidation of δ-hydroxy allylic phosphine oxides 5 with m-CPBA can be syn selective.All stereoisomers of epoxy alcohols 6 are available when this method is used in tandem with an anti selective Sharpless kinetic resolution.The stereoisomers of epoxy alco

Asymmetric epoxidations and kinetic resolutions of δ-hydroxy allylic phosphine oxides

δ-Hydroxy allylic phosphine oxides 5 undergo asymmetric epoxidation to yield epoxy alcohols 6 with high enantio- and diastereoselectivity. Kinetic resolutions are also successful, even with a chiral centre remote from the allylic hydroxyl, if that chiral