1456706-40-3

Upstream product

• 123-35-3 7-methyl-3-methene-1,6-octadiene 
• 874584-13-1 5,5-dimethyl-5,6,7,8-tetrahydro-1,4-anthraquinone 
• 177327-03-6 6-(2-(3,3-dimethylpropoxycarbonyl-2-yl)ethyl)naphthalene-1,4-dione 
• 915093-55-9 2,3-dichloro-5,5-dimethyl-5,6,7,8-tetrahydro-anthracene-1,4-dione 
• 6315-89-5 3,4-dimethoxyaniline 

Relevant academic research and scientific papers

New 1,4-anthracenedione derivatives with fused heterocyclic rings: Synthesis and biological evaluation

Several terpenylquinones derived from 1,4-anthracenedione (1,4-anthracenequinone, AQ) have been prepared by addition or substitution nucleophilic reactions and further transformed into extended polycyclic systems, which mainly kept the 1,4-quinone moiety fused to different nitrogen-heterocyclic rings (pyrrole, imidazole, pyrazine or quinoxaline) into the structure. The compounds synthesized were evaluated for their antineoplastic, antifungal and antiviral activities. GI50 antineoplastic values remained under μM levels for AQs, while the heterocyclic derivatives showed antifungal MIC values in the low μg mL-1 range against yeasts and filamentous fungi. Only few compounds displayed a discrete non-selective antiherpetic activity in the μg mL-1 range. This journal is

Synthesis and antifungal activity of terpenyl-1,4-naphthoquinone and 1,4-anthracenedione derivatives

The antifungal evaluation of twenty seven simple and heterocycle-fused prenyl-1,4-naphthoquinones and 1,4-anthracenediones was performed in vitro against human pathogenic yeasts (Candida spp.) and filamentous fungi (Aspergillus spp., Fusarium spp., and Tr