1456713-16-8

Basic information

• Product Name: 2-[(1R,2R)-2-[(diphenylphosphoroso)amino]-1,2-diphenylethyl]-2,3-dihydro-1H-isoindole-1,3-dione
• Synonyms: 2-[(1R,2R)-2-[(diphenylphosphoroso)amino]-1,2-diphenylethyl]-2,3-dihydro-1H-isoindole-1,3-dione
• CAS NO: 1456713-16-8
• Molecular Weight: 542.574
• Mol File: 1456713-16-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[(1R,2R)-2-[(diphenylphosphoroso)amino]-1,2-diphenylethyl]-2,3-dihydro-1H-isoindole-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(1R,2R)-2-[(diphenylphosphoroso)amino]-1,2-diphenylethyl]-2,3-dihydro-1H-isoindole-1,3-dione(1456713-16-8)
• EPA Substance Registry System: 2-[(1R,2R)-2-[(diphenylphosphoroso)amino]-1,2-diphenylethyl]-2,3-dihydro-1H-isoindole-1,3-dione(1456713-16-8)

Safety Data

• Hazardous Substances Data: 1456713-16-8(Hazardous Substances Data)

Upstream product

• 35132-20-8 (R,R)-1,2-diphenylethylenediamine 
• 1387581-28-3 2-[(1R,2R)-2-amino-1,2-diphenylethyl]-2,3-dihydro-1H-isoindole-1,3-dione 
• 1499-21-4 Diphenylphosphinic chloride 
• 85-44-9 phthalic anhydride 

Downstream Products

• 511534-46-6 [(1R,2R)-2-amino-1,2-diphenylethyl](diphenylphosphoroso)amine 
• 1456713-21-5 [(1R,2R)-2-[(diphenylphosphoroso)amino]-1,2-diphenylethyl](propan-2-yl)amine 
• 1456713-20-4 [(1R,2R)-2-(cyclohexylamino)-1,2-diphenylethyl](diphenylphosphoroso)amine 
• 1456713-23-7 (butan-2-yl)[(1R,2R)-2-[(diphenylphosphoroso)amino]-1,2-diphenylethyl]amine 

Relevant articles and documents

QSAR analysis of the catalytic asymmetric ethylation of ketone using physical steric parameters of chiral ligand substituents

We have demonstrated that a validated QSAR (quantitative structure-activity relationship) model can be constructed between sterimol steric parameters of the N-substituents of chiral 1,2-amino-phosphoramide ligands and the enantiomeric ratios of alcohol products produced in the asymmetric additions of diethylzinc to acetophenone, which is powerful for predicting the steric effects of ligand substituents on enantioselectivities and instructive for ligand optimization.