145678-47-3

Basic information

• Product Name: Butanedioic acid, hydroxy-, dipropyl ester, (2S)-
• CAS NO: 145678-47-3
• Molecular Formula: C10H18O5
• Mol File: 145678-47-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Butanedioic acid, hydroxy-, dipropyl ester, (2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanedioic acid, hydroxy-, dipropyl ester, (2S)-(145678-47-3)
• EPA Substance Registry System: Butanedioic acid, hydroxy-, dipropyl ester, (2S)-(145678-47-3)

Safety Data

• Hazardous Substances Data: 145678-47-3(Hazardous Substances Data)

Upstream product

• 71-23-8 propan-1-ol 
• 97-67-6 (S)-Malic acid 

Relevant articles and documents

Enantiomerically pure tetrahydro-5-oxo-2-furancarboxylic esters from dialkyl 2-oxoglutarates

Enantiomerically pure tetrahydro-5-oxo-2-furancarboxylic esters can be prepared either by enzymatic resolution of the racemic γ-lactones themselves or by bioreduction with baker's yeast of dialkyl 2-oxoglutarates and subsequent cyclization of the resulting dialkyl 2-hydroxyglutarates. The best results were obtained by the former route, by which the desired compounds were isolated in high enantiomeric excess. Bioreductions were less satisfactory. In fact the hydroxyester intermediates were initially formed as racemic mixtures and their final enantiomeric enrichment was reached by asymmetric destruction, occurring in the bioreaction medium, however at the same time large amounts of alkyl 4-hydroxybutanoates were formed as side products.