1456785-17-3Relevant academic research and scientific papers
Copper on iron promoted one-pot synthesis of β-aminoenones and 3,5-disubstituted pyrazoles
Kovács, Szabolcs,Novák, Zoltán
, p. 8987 - 8993 (2013)
The reaction of hydroximoyl chlorides with acetylenes in the presence of a copper on iron bimetallic system leads to β-aminoenones via reductive ring opening of isoxazole intermediates. The valuable β-aminoenone building blocks can be isolated or transformed into pyrazoles with the addition of hydrazine in a straightforward one-pot procedure.
