1456889-22-7

Upstream product

• 125878-02-6 2-((2R,3S)-3-(tert-butyldimethylsiloxy)tetrahydropyran-2-yl)acetaldehyde 
• 1456888-93-9 (((2R,3S)-2-((S)-2-(oxy)penta-3,4-dien-1-yl)tetrahydro-2H-pyran-3-yl)oxy)(tert-butyl)dimethylsilane 
• 100-39-0 benzyl bromide 
• 1456888-89-3 (S)-1-((2R,3S)-3-((tert-butyldimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)-3-(trimethylsilyl)penta-3,4-dien-2-ol 

Downstream Products

• 1456888-96-2 (2R,3S)-2-((S)-2-(benzyloxy)penta-3,4-dien-1-yl)tetrahydro-2H-pyran-3-ol 
• 1456888-98-4 (2R,3S,4aR,8aS)-3-(benzyloxy)-2-vinyloctahydropyrano[3,2-b]pyran 

Relevant academic research and scientific papers

Synthesis of fused tetrahydropyrans by hydroalkoxylation of δ-hydroxy allenes

Fused tetrahydropyrans were synthesized by silver(I)- and mercury(II)-mediated intramolecular hydroalkoxylations of δ-hydroxy allenes installed on a tetrahydropyran template. Cyclization of simple allenes was promoted by silver perchlorate to afford vinyl-substituted trans-fused bis-tetrahydropyrans, whereas cyclization of methyl-substituted allenes at the internal allenic carbon atom was achieved more effectively with a catalytic amount of mercuric triflate rather than with silver salts.