1456898-36-4

Upstream product

• 99-20-7 TREHALOSE 
• 1456898-37-5 4,6;4′,6′-di-O-(p-methoxybenzylidene)-α,α-D-trehalose 
• 824-94-2 p-methoxybenzyl chloride 
• 2186-92-7 p-Anisaldehyde dimethyl acetal 

Downstream Products

• 1456898-38-6 2,3,4,2',3'-penta-O-(p-methoxybenzyl)-4',6'-O-(p-methoxybenzylidene)-α,α-D-trehalose 
• 1456898-39-7 2,3,4,2',3',4'-hexa-O-(p-methoxybenzyl)-α,α-D-trehalose 

Relevant academic research and scientific papers

Crystal-to-Crystal Synthesis of Helically Ordered Polymers of Trehalose by Topochemical Polymerization

The synthesis of crystalline helical polymers of trehalose via topochemical azide–alkyne cycloaddition (TAAC) of a trehalose-based monomer is presented. An unsymmetrical trehalose derivative having azide and alkyne crystallizes in two different forms havi

Desymmetrization of trehalose via regioselective DIBAL reductive ring opening of benzylidene and substituted benzylidene acetals

Trehalose dibenzylidene and substituted dibenzylidene acetals were reductively opened either at O6 or O4 in a regioselective manner by using a DIBAL stock solution prepared in toluene or dichloromethane, respectively, to achieve desymmetrization of the trehalose core. The method was applied to synthesize various biologically important unsymmetrically substituted trehalose glycoconjugates, including a mycobacterial trisaccharide, a 4-epi-trehalosamine analog and a maradolipid.