1456907-32-6

Basic information

• Product Name: 2-[N-(4-phenylbenzenecarbonyl)amino]-6-(trans-2-phenylcyclopropane-1-amino)-N-(3-phenylbenzyl)hexanamide trifluoroacetate
• Synonyms: 2-[N-(4-phenylbenzenecarbonyl)amino]-6-(trans-2-phenylcyclopropane-1-amino)-N-(3-phenylbenzyl)hexanamide trifluoroacetate
• CAS NO: 1456907-32-6
• Molecular Weight: 721.819
• Mol File: 1456907-32-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[N-(4-phenylbenzenecarbonyl)amino]-6-(trans-2-phenylcyclopropane-1-amino)-N-(3-phenylbenzyl)hexanamide trifluoroacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[N-(4-phenylbenzenecarbonyl)amino]-6-(trans-2-phenylcyclopropane-1-amino)-N-(3-phenylbenzyl)hexanamide trifluoroacetate(1456907-32-6)
• EPA Substance Registry System: 2-[N-(4-phenylbenzenecarbonyl)amino]-6-(trans-2-phenylcyclopropane-1-amino)-N-(3-phenylbenzyl)hexanamide trifluoroacetate(1456907-32-6)

Safety Data

• Hazardous Substances Data: 1456907-32-6(Hazardous Substances Data)

Upstream product

• 1456906-30-1 2-(N-tert-butoxycarbonylamino)-6-(trans-2-phenylcyclopropan-1-amino)-N-(3-phenylbenzyl)hexanamide 
• 1456906-14-1 2-(N-tert-butoxycarbonylamino)-6-(O-methanesulfonyl)-N-(3-phenylbenzyl)hexanamide 
• 1456906-01-6 2-(N-tert-butoxycarbonylamino)-6-hydroxy-N-(3-phenylbenzyl)hexanamide 
• 1456905-86-4 6-amino-2-(N-tert-butoxycarbonylamino)-N-(3-phenylbenzyl)hexanamide 
• 1456905-78-4 6-(N-benzyloxycarbonylamino)-2-(N-tert-butoxycarbonylamino)-N-(3-phenylbenzyl)hexanamide 
• 177976-49-7 3-phenylbenzylamine 
• 76-05-1 trifluoroacetic acid 
• 92-92-2 biphenyl-4-carboxylic acid 
• 2389-45-9 Boc-Lys(Z)-OH 

Relevant articles and documents

Lysine-specific demethylase 1-selective inactivators: Protein-targeted drug delivery mechanism

Drug drop off: Given that lysine-specific demethylase 1 (LSD1) could be potently and selectively inactivated by delivering phenylcyclopropylamine (PCPA), a weak and nonselective LSD1 inhibitor, directly to the enzyme's active site, a novel series of LSD1 inactivators (1) were designed. Biological and mechanistic studies indicate that 1 inhibits LSD1 potently and selectively. Copyright