1456928-97-4

Upstream product

• 1380917-35-0 5-bromo-3-iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole 
• 459133-66-5 5-bromo-3-iodo-1H-indazole 
• 53857-57-1 5-bromo-1H-indazole 
• 1456928-96-3 ethyl 4-(3-(4-hydroxyphenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-5-yl) benzoate 
• 1456928-95-2 4-(5-bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl) phenol 

Downstream Products

• 1456928-83-8 C₂₀H₁₄N₂O₃ 
• 1456928-84-9 (4-(3-(4-hydroxyphenyl)-1H-indazol-5-yl)phenyl)(piperazin-1-yl)methanone 
• 1456928-85-0 (4-(3-(4-hydroxyphenyl)-1H-indazol-5-yl)phenyl)(4-methylpiperazin-1-yl)methanone 
• 1456928-87-2 4-(3-(4-hydroxyphenyl)-1H-indazol-5-yl)-N-(3-(trifluoromethyl)phenyl)benzamide 
• 1456928-88-3 4-(3-(4-hydroxyphenyl)-1H-indazol-5-yl)-N-(4-methylthiophen-2-yl)benzamide 
• 1456928-89-4 (4-(3-(4-hydroxyphenyl)-1H-indazol-5-yl)phenyl)(piperidin-1-yl)methanone 
• 1456928-90-7 C₂₄H₂₁N₃O₃ 
• 1456928-91-8 (4-(3-(4-hydroxyphenyl)-1H-indazol-5-yl)phenyl)(pyrrolidin-1-yl)methanone 
• 1456928-92-9 methyl 1-(4-(3-(4-hydroxyphenyl)-1H-indazol-5-yl)(benzoyl)(pyrrolidine))-2-carboxylate 
• 1456928-94-1 1-(4-(3-(4-hydroxyphenyl)-1H-indazol-5-yl)benzoyl)pyrrolidine-2-carboxylic acid 

Relevant academic research and scientific papers

Synthesis and antimicrobial screening of novel 3, 5-disubstituted indazole derivatives

Amine coupling strategy was developed for the synthesis of new indazole derivatives through reaction of 4-(3- (4-hydroxyphenyl)-1-(tetrahydro-2H-pyran- 2-yl)-1H-indazol-5-yl) benzoic acid 19 with amines 20a-i. All the newly synthesized compounds were screened for their antimicrobial and antifungal activities. Among the several compounds synthesized (4-(3-(4-hydroxyphenyl)-1H- indol-5-yl)phenyl)(piperazin-1-yl)methanone 2, (4-(3-(4-hydroxyphenyl)- 1Hindazol- 5-yl)phenyl)(4-methylpiperazin-1-yl)methanone 3, 1-(4-(4-(3-(4- hydroxyphenyl)-1H-indol-5-yl) benzoyl) piperazin- 1-yl) ethanone 4 and (4-(3-(4-hydroxyphenyl)-1H-indol-5-yl) phenyl)(pyrrolidin-1-yl)methanone 9 showed potential activities against a variety of bacterial and fungal strains.