145693-90-9Relevant academic research and scientific papers
An Improved Protocol for Synthesis of 3-Substituted 5-Arylidene-2-thiohydantoins: Two-step Procedure Alternative to Classical Methods
Kuznetsova, Olga Yu,Antipin, Roman L.,Udina, Anna V.,Krasnovskaya, Olga O.,Beloglazkina, Elena K.,Terenin, Vladimir I.,Koteliansky, Victor E.,Zyk, Nikolay V.,Majouga, Alexander G.
, p. 1570 - 1577 (2016/09/24)
A novel method for the direct synthesis of 5-arylidene-2-thiohydantoins from thioureas and aromatic aldehydes in the presence of base in ethanol was developed. Application of this efficient method allowed preparing thiohydantoins, which are difficult to s
Synthesis of isomeric 3-phenyl-5-(pyridylmethylene)-2-thiohydantoins and their S-methylated derivatives. Molecular and crystal structures of (5Z)-3-phenyl-5-(pyridin-2-ylmethylene)-2-thiohydantoin and (5Z)-2-methylthio-3- phenyl-5-(pyridin-2-ylmethylene)-
Majouga,Beloglazkina,Vatsadze,Frolova,Zyk
, p. 2850 - 2855 (2007/10/03)
Three procedures were used for the synthesis of α-, β, and γ-pyridyl-substituted (5Z)-3-phenyl-5-(pyridylmethylene)-2-thiohydantoins: the reaction of 2-thiohydantoin with the corresponding aldehyde in AcOH in the presence of AcONa, the two-step one-pot sy
Study of 5-arylidene-2-thiohydantoins with potential immunomodulating and anticancer activities
Chazeau, V,Cussac, M,Boucherle, A
, p. 615 - 625 (2007/10/02)
Various 5-arylidene-2-thiohydantoins, N3-substituted and/or S-substituted or not, were synthesized by aldolisation-crotonisation reaction from aromatic aldehydes or cyclic ketones and 2-thiohydantoins. These products, largely original, prepared as potenti
