145694-42-4Relevant academic research and scientific papers
Facile enzymatic preparation for enantiomeric β-lactams
Nagai,Shiozawa,Achiwa,Terao
, p. 2227 - 2229 (1992)
Optically active β-lactams were obtained conveniently by lipase-catalyzed enantioselective hydrolysis of 1-acyloxymethyl-2-azetidinones and esterification of 1-hydroxymethyl-3,3-dimethyl-2-azetidinone with vinyl acetate in organic solvent.
Convenient syntheses of optically active β-lactams by enzymatic resolution
Nagai,Shiozawa,Achiwa,Terao
, p. 1933 - 1938 (2007/10/02)
Optically active β-lactams were synthesized by lipase-catalyzed kinetic resolution using the enantioselective hydrolysis of N-acyloxymethyl β- lactams (3) in an organic solvent and the transesterification of N- hydroxymethyl β-lactams (2) with vinyl aceta
