145694-86-6Relevant academic research and scientific papers
Interaction of 2-bromo-7-methyl-5-oxo-5H-1,3,4-thiadiazolopyrimidine with methylene-active compounds and acid hydrolysis of its products
Shukurov, S. S.,Kukaniev, M. A.,Nasyrov, I. M.,Zakharov, K. S.,Karakhanov, R. A.
, p. 1874 - 1878 (1993)
Reactions of 2-bromo-7-methyl-5-oxo-5H-1,3,4-thiadiazolopyrimidine with sodium derivatives of pentane-2,4-dione, malonodinitrile, Meldrum acid, acetoacetic, cyanoacetic and malonic esters have been shown to give the respective substituted derivatives.Azinyl-ylidene tautomerism has been found to be characteristic of these compounds, the latter existing mainly in the ylidene form.The acid hydrolysis of pentane-2,5-dione and cyanoacetic acid and malonic esters derivatives has been onvestigated. - Key words: nucleophilic substitution reaction, 2-bromo-7-methyl-5-oxo-5H-1,3,4-thiadiazolopyrimidine, methylene active compounds (pentane-2,5-dione, malonodinitrile, Meldrum acid, acetoacetic, cyanoacetic, malonic esters), azinyl-ylidene tautomerism, ketonic and acidic cleavage.
