145772-63-0Relevant academic research and scientific papers
Total Synthesis of 5-Hydroxygoniothalamin
Patpi, Santhosh Reddy,Jin, Guangyi,Kantevari, Srinivas
, p. 780 - 786 (2019/01/23)
The total synthesis of 5-hydroxygoniothalamin is achieved from commercially available l -xylose. The α,β-unsaturated-δ-lactone core is constructed in very good yield by utilizing one-carbon and two-carbon cis -Wittig olefinations and δ-lactonization using Yamaguchi conditions. Subsequent Grubbs cross-metathesis followed by desilylation results in 5-hydroxygoniothalamin.
Tetrofuranose nucleoside phosphonic acids: Synthesis and properties
Polakova, Ivana,Budesinsky, Milos,Tocik, Zdenek,Rosenberg, Ivan
, p. 503 - 536 (2011/12/04)
New isoelectronic, non-isosteric phosphonate analogues of nucleoside 5'-phosphates featuring the phosphorus moiety directly attached on the sugar ring in the C4' position are described. The analogues were synthesised by a nucleosidation reaction from tetr
First stereocontrolled synthesis and biological evaluation of 1,6-dideoxy-L-nojirimycin
Bordier, Aymeric,Compain, Philippe,Martin, Olivier R.,Ikeda, Kyoko,Asano, Naoki
, p. 47 - 51 (2007/10/03)
The first synthesis of 1,6-dideoxy-L-nojirimycin in enantiomerically pure form has been achieved in nine steps from L-xylose in an overall yield of 15%. The biological activity of this compound as a glycosidase inhibitor provided useful information on str
