145782-08-7

Basic information

• Product Name: cis-1-acetyl-4-<-<<2-(1,1'-biphenyl-4-yl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl>methoxy>phenyl>piperazine
• CAS NO: 145782-08-7
• Molecular Weight: 538.646
• Mol File: 145782-08-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: cis-1-acetyl-4-<-<<2-(1,1'-biphenyl-4-yl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl>methoxy>phenyl>piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: cis-1-acetyl-4-<-<<2-(1,1'-biphenyl-4-yl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl>methoxy>phenyl>piperazine(145782-08-7)
• EPA Substance Registry System: cis-1-acetyl-4-<-<<2-(1,1'-biphenyl-4-yl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl>methoxy>phenyl>piperazine(145782-08-7)

Safety Data

• Hazardous Substances Data: 145782-08-7(Hazardous Substances Data)

Upstream product

• 145782-17-8 (+/-)-trans-[2-(1,1'-biphenyl-4-yl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl methanesulfonate 
• 67914-60-7 N-acetyl-N'-(4-hydroxyphenyl)piperazine 
• 133345-21-8 1-(4-Acetoxyphenyl)-4-acetylpiperazine 
• 145782-11-2 cis/trans-<2-(1,1'-biphenyl-4-yl)-2-bromomethyl-1,3-dioxolan-4-yl>methyl benzoate 
• 145782-17-8 cis-<2-(1,1'-biphenyl-4-yl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl>methyl methanesulfonate 
• 145782-12-3 cis-<2-(1,1'-biphenyl-4-yl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl>methyl benzoate 
• 145782-15-6 cis-<2-(1,1'-biphenyl-4-yl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl>methanol 
• 145782-10-1 cis/trans-<2-(1,1'-biphenyl-4-yl)-2-bromomethyl-1,3-dioxolan-4-yl>methanol 
• 135-73-9 2-Bromo-4'-phenylacetophenone 
• 38869-37-3 1-(4-hydroxy-phenyl)-piperazine dihydrobromide 
• 38212-30-5 4-(4-methoxyphenyl)piperazine 
• 145782-12-3 trans-<2-(1,1'-biphenyl-4-yl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl>methyl benzoate 
• 145782-15-6 trans-<2-(1,1'-biphenyl-4-yl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl>methanol 

Relevant articles and documents

Synthesis and antifungal activity of structural analogues of bifonazole and ketoconazole

The synthesis and antifungal activities of the cis- and trans-1-acetyl-4-[4-[[2-(1,1'-biphenyl-4-yl)-2-(1H-imidazol-l-ylmethyl )-1,3-dioxolan-4-yl]-methoxy]phenyl]piperazines 3 and 4 are reported. Stereochemical assignments to diastereomeric pairs of cis/trans isomers were made on the basis of 1H and 13C-NMR data. Among test derivatives the best activity was shown by the benzoyl esters of the cis- and trans-[2-(1,1'-biphenyl-4-yl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan- 4-yl]methanols 9 and 10.