145798-90-9

Upstream product

• 20231-36-1 methyl 6-O-trityl-α-D-mannopyranoside 
• 617-04-9 (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-methoxytetrahydro-2H-pyran-3,4,5-triol 
• 16802-89-4 methyl 2,3-di-O-mesyl-6-O-trityl-α-D-mannopyranoside 
• 118360-82-0 methyl 2,4-dibromo-2,4-dideoxy-6-O-triphenylmethyl-α-D-idopyranoside 
• 118360-83-1 methyl 2,3-anhydro-4-bromo-4-deoxy-6-O-trityl-α-D-gulopyranoside 
• 118360-81-9 methyl 4-bromo-2,4-dideoxy-2-C-methyl-6-O-triphenylmethyl-α-D-idopyranoside 
• 118360-84-2 methyl 3,4-anhydro-2-deoxy-2-C-methyl-6-O-trityl-α-D-altropyranoside 
• 76-83-5 trityl chloride 
• 100-39-0 benzyl bromide 
• 68880-92-2 methyl 2,3-dideoxy-2-C-methyl-6-O-(triphenylmethyl)-α-D-arabino-hexopyranoside 
• 118360-80-8 methyl 3,4-anhydro-2-O-mesyl-6-O-trityl-α-D-altropyranoside 

Downstream Products

• 137822-27-6 methyl 4-O-benzyl-2,3-dideoxy-2-C-methyl-α-D-arabino-hexopyranoside 
• 137788-12-6 (2S,3R,4S,6S)-4-benzyloxy-2,6-dimethyl-1,3,7-heptanetriol 
• 137788-12-6 (2R,3R,4S,6S)-4-benzyloxy-2,6-dimethyl-1,3,7-heptanetriol 
• 145798-82-9 (2S,3R,4S,6S)-1,3-(benzylidendioxy)-4-benzyloxy-7-<4-(methoxybenzyl)oxy>-2,6-dimethylheptane 
• 137788-13-7 (2S,4S,5R,6S)-5,7-(benzylideneedioxy)-4-benzyloxy-2,6-dimethyl-1-heptanol 
• 137788-10-4 methyl 4-O-benzyl-2,3,7-trideoxy-2-C-methyl-α-D-arabino-heptapyranosid-6-ulose 
• 137964-43-3 methyl 4-O-benzyl-2,3,6,7-tetradeoxy-2,6-di-O-C-methyl-α-D-arabino-hept-6-enopyranoside 
• 145798-92-1 (2S,3R,4S,6S)-7-(4-Methoxy-benzyloxy)-2,6-dimethyl-heptane-1,3,4-triol 
• 145798-81-8 1-((2R,3S,5S,6S)-3-Benzyloxy-6-methoxy-5-methyl-tetrahydro-pyran-2-yl)-ethanol 
• 137788-11-5 (2S,4S,5R)-4-benzyloxy-2,6-dimethyl-6-heptene-1,5-diol 

Relevant academic research and scientific papers

The first total synthesis of calbistrin A, a microbial product possessing multiple bioactivities

The octahydronaphthopyranone moiety is synthesized from methyl α-D-mannopyranoside through the intramolecular Diels-Alder reaction, and the tetraenedicarboxylic acid moiety is from the enzymatically prepared anti-compound. Both moieties were coupled to accomplish the total synthesis of calbistrin A and to disclose its absolute structure.

Total synthesis of herbimycin A

The first total synthesis of herbimycin A (1), the benzoquinoid ansamycin antibiotic, has been accomplished by coupling two segments of the aliphatic ansa-chain 2 and the aromatic chromophore 3, elucidating the absolute stereochemistry.