1458-19-1

Usage

Uses

Used in Pharmaceutical Industry:
METHYL 3,5-DIAMINOPYRAZINE-2-CARBOXYLATE is used as a building block for the synthesis of various drugs and pharmaceuticals, contributing to the development of new medications and therapies.
Used in Organic Chemistry and Research:
METHYL 3,5-DIAMINOPYRAZINE-2-CARBOXYLATE is used as a starting material in the preparation of other complex organic compounds, facilitating advancements in chemical research and the creation of novel organic substances.

Upstream product

• 1458-01-1 3,5-diamino-6-chloro-pyrazine-2-carboxylic acid methyl ester 

Downstream Products

• 135673-72-2 3,5-Diamino-6-benzoyl-pyrazine-2-carboxylic acid methyl ester 
• 135673-70-0 6-Acetyl-3,5-diamino-pyrazine-2-carboxylic acid methyl ester 
• 135673-73-3 3,5-diamino-6-(α-hydroxybenzyl)-2-pyrazinecarboxylate 
• 146940-44-5 6-Benzoylamiloride 
• 146940-45-6 6-(1-Hydroxybenzyl)amiloride 
• 39939-29-2 3,5-Diamino-pyrazinsaeure 
• 1135686-60-0 methyl 3,5-diamino-6-phenylpyrazine-2-carboxylate 
• 1345839-39-5 C₁₂H₁₃N₇O*ClH 
• 1345839-41-9 C₁₄H₁₃N₇O*ClH 
• 146940-41-2 Methyl 3,5-diamino-6-phenylethinylpyrazine-2-carboxylate 

Relevant academic research and scientific papers

Synthesis and preliminary evaluation of amiloride analogs as inhibitors of the urokinase-type plasminogen activator (uPA)

A known side-activity of the oral potassium-sparing diuretic drug amiloride is inhibition of the enzyme urokinase-type plasminogen activator (uPA, K i = 7 μM), a promising anticancer target. Several studies have demonstrated significant antitum

NOVEL ANTIMALARIA AGENT CONTAINING HETEROCYCLIC COMPOUND

Disclosed is an antimalarial agent containing a compound represented by the formula: [wherein A1 represents a 3-pyridyl group that may have a substituent, a 6-quinolyl group that may have a substituent, or the like; X1 represents a group represented by the formula -C(=O)-NH- or the like; E represents a furyl group, a thienyl group or a phenyl group; with the proviso that A1 may have one to three substituents, and E has one of two substituents] or a salt thereof or hydrates thereof.

NOVEL ANTIFUNGAL AGENT COMPRISING HETEROCYCLIC COMPOUND

The present invention provides an antifungal agent represented by the formula: [wherein A1 represents a 3-pyridyl group which may have a substituent, a quinolyl group which may have a substituent, or the like; X1 represents a group represented by the formula -NH-C(=O)-, a group represented by the formula -C(=O)-NH-, or the like; E represents a furyl group, a thienyl group, a pyrrolyl group, a phenyl group, a pyridyl group, a tetrazolyl group, a thiazolyl group or a pyrazolyl group; with the proviso that A1 may have 1 to 3 substituents, and E has one or two substituents].