145800-57-3

Upstream product

• 1826-67-1 vinyl magnesium bromide 
• 139240-50-9 (S)-(-)-2-methyl-2-(p-tolyl)cyclobutanone 
• 95631-61-1 2-methyl-2-(p-tolyl)cyclobutanone 

Downstream Products

• 145842-59-7 (1S,3S)-3-methyl-2-methylene-3-p-tolylcyclopentanol 
• 145800-61-9 (1R,3S)-3-methyl-2-methylene-3-p-tolylcyclopentanol 
• 145800-62-0 (1S,3S)-3-methyl-2-methylene-3-p-tolylcyclopentyl benzoate 
• 145800-63-1 (1S,2R,3S)-2,3-dimethyl-3-p-tolylcyclopentyl benzoate 
• 145800-59-5 (R)-2-Hydroxymethyl-3-methyl-3-p-tolyl-cyclopentanone 
• 145842-60-0 (1S,2R,3S)-2,3-dimethyl-3-p-tolylcyclopentanol 
• 93862-62-5 (3S)-3-methyl-2-methylene-3-p-tolylcyclopentanone 
• 130398-94-6 (1R)-1,2-dimethyl-1-p-tolylcyclopentane 
• 22489-30-1 (2R,3R)-2,3-dimethyl-3-p-tolylcyclopentanone 
• 18452-41-0 (+)-laurene 
• 145800-58-4 (1S,2S)-1-(1,2-epoxyethyl)-2-methyl-2-p-tolylcyclobutanol 
• 145800-60-8 (1R,2S)-2-methyl-2-p-tolyl-1-triethylsiloxy-1-vinylcyclobutane 

Relevant academic research and scientific papers

Chiral Cyclobutanones as Versatile Synthons: the First Enantioselective Total Synthesis of (+)-Laurene

A novel and convenient route to the thermodynamically unstable ketone 11 via the cyclopentanone 8 which was synthesised by palladium-mediated ring expansion of the chiral siloxyvinylcyclobutanes 9 and 10 has been developed.This leads to an enantioselectiv

The First Enantioselective Total Synthesis of (+)-Laurene

The cyclopentenone 8, synthesized by palladium mediated ring expansion of the chiral vinylcyclobutanols 3 and 4, is converted to the thermodynamically unstable ketone 16 which on methylenation gives (+)-laurene 1.