145836-07-3

Upstream product

• 1214-98-8 phenyl 1-thio-α-L-rhamnopyranose 
• 98-88-4 benzoyl chloride 
• 707-07-3 orthobenzoic acid trimethyl ester 
• 145836-08-4 phenyl 4-O-benzoyl-2,3-O-isopropylidene-1-thio-α-L-rhamnopyranoside 
• 940006-51-9 S-phenyl 3-O-(2-naphthylmethyl)-α-L-thiorhamnopyranoside 
• 108740-74-5 phenyl 2,3,4-tri-O-acetyl-1-thio-α-L-rhamnopyranoside 
• 145836-09-5 phenyl 4-O-benzoyl-1-thio-α-L-rhamnopyranoside 
• 131087-35-9 phenyl 2,3-O-isopropylidene-1-thio-α-L-rhamnopyranoside 

Downstream Products

• 142967-72-4 2,4-di-O-benzoyl-3-O-bromoacetyl-α-L-rhamnopyranosyl chloride 
• 952575-81-4 phenyl 2-O-benzyl-3,5-O-(di-tert-butylsilane-diyl)-β-L-arabinofuranosyl-(1->3)-2,4-di-O-benzoyl-1-thio-α-L-rhamnopyranoside 
• 1191079-96-5 phenyl 2-O-acetyl-3,4-di-O-benzoyl-α-L-rhamnopyranosyl-(1->3)-2,4-di-O-benzoyl-1-thio-α-L-rhamnopyranoside 

Relevant academic research and scientific papers

A simple method for avoiding alkylthio group migration during the synthesis of thioglycoside 2,3-orthoesters. An improved synthesis of partially acylated 1-thio-α-L-rhamnopyranosides

A fast, technically simple and high-yielding procedure is described for the preparation of the 2,3-cyclic orthoesters of methyl, ethyl, and phenyl 1-thio-α-L-rhamnopyranosides. The method prevents alkylthio group migration during the synthesis of thioglycoside 2,3-orthoesters. Considering the high yields, short reaction times and operational simplicity, this method is a substantial improvement over the procedures previously proposed for the synthesis of partially acylated 1-thio-α-L-rhamnopyranosides.