145846-67-9

Upstream product

• 64569-68-2 L-leucine-N-methylamide 
• 145846-65-7 (S)-5-Isobutyl-2,2,3-trimethyl-imidazolidin-4-one 
• 25726-04-9 phenylglyoxylyl chloride 
• 145846-66-8 1-((S)-5-Isobutyl-2,2,3-trimethyl-4-oxo-imidazolidin-1-yl)-2-phenyl-ethane-1,2-dione 

Relevant academic research and scientific papers

Influence des ultrasons sur la diastereoselectivite. Synthese d'imidazolidine-4-one chirales

A three-step synthesis of imidazolidine-4-one has been realized.Sodium dithionite was a very efficient reagent for the last step, the reduction of a ketone.The reaction is slow under the normal conditions of heating and its diastereoselectivity is poor.Un

5-Substituted (5S)-Imidazolidin-4-ones as Effective Chiral Auxiliary for Hydrogenation of α-Keto Amides

The title chiral auxiliary was used for asymmetric catalytic hydrogenation of amides derived from phenylglyoxylic acid to give mandelamides with high diastereoselectivity (diastereosisomeric excess, d.e. up to 96percent). Keywords.Asymmetric hydrogenation