145850-64-2Relevant academic research and scientific papers
CATYLYTIC SYNTHESIS AND REACTIONS OF MAGNESIOCYCLOALKANES. 2. SYNTHESIS OF SUBSTITUTED MAGNESIOCYCLOPENTANES IN THE PRESENCE OF ZYRCONIUM COMPLEXES
Dzhemilev, U. M.,Sultanov, R. M.,Gaimaldinov, R. G.,Muslukhov, R. R.,Lomakina, S. I.,Tolstikov, G. A.
, p. 770 - 788 (2007/10/02)
Catalytic cyclometallation of styrene, m-methylstyrene, p-tert-butylstyrene, and 1-hexene with di n-alkylmagnesium compounds (n-R2Mg, where R=C3H7, C4H9, C6H13) in the presence of Cp2Zr2Cl2 has been given high yields of 2,4-disubstituted magnesiocyclopentanes.The probable mode of formation of magnesiocyclopentanes, involving zirconocyclopentanes formed from Cp2ZrCl2, n-R2Mg, and the appropiate olefins as reactive intermediates in the cyclometallation, is discussed. Keywords: catalytic synthesis, substituted styrenes, alkenes, magnesium alkyls.
Regioselective and Diastereoselective Alkyl-Alkene and Alkene-Alkene Coupling Promoted by Zirconocene and Hafnocene
Swanson, Douglas R.,Rousset, Christophe J.,Negishi, Ei-ichi,Takahashi, Tamotsu,Seki, Takashi,et al.
, p. 3521 - 3523 (2007/10/02)
The reaction of Cp2Zr(CH2CH2R1)2 with a monosubstituted terminal alkene (H2C=CHR2) can produce, in a highly regio- and diastereoselective manner, zirconacyclopentane derivatives; the trans-3,4-disubstituted derivatives may be formed to the extents of >98percent in cases where both R1 and R2 are alkyl, while the trans-2-aryl-4-alkyl derivatives may be formed to the extents of >98percent in the coupling between a monoalkyl-substituted olefin and styrene or its derivative.
