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145914-06-3

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145914-06-3 Usage

General Description

1,1,1-trifluoro-2-(2-nitrophenyl)ethane, also known as 1,1,1-trifluoro-2-(2-nitrophenyl)ethane, is a chemical compound with the molecular formula C8H6F3NO2. It is a colorless liquid that is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 1,1,1-trifluoro-2-(2-nitrophenyl)ethane is also used in the production of dyes and pigments, as well as in the manufacture of other specialty chemicals. Additionally, 1,1,1-trifluoro-2-(2-nitrophenyl)ethane is a potent greenhouse gas and is considered to be a significant contributor to global warming. Therefore, its use and production are regulated in many countries to mitigate its environmental impact.

Check Digit Verification of cas no

The CAS Registry Mumber 145914-06-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,9,1 and 4 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 145914-06:
(8*1)+(7*4)+(6*5)+(5*9)+(4*1)+(3*4)+(2*0)+(1*6)=133
133 % 10 = 3
So 145914-06-3 is a valid CAS Registry Number.

145914-06-3Downstream Products

145914-06-3Relevant articles and documents

Metal-Free Construction of the C(sp3)-CF3 Bond: Trifluoromethylation of Hydrazones with Togni's Reagent under Mild Conditions

Zeng, Huiying,Luo, Zhen,Han, Xinlong,Li, Chao-Jun

supporting information, p. 5948 - 5951 (2019/08/29)

A metal-free trifluoromethylation of hydrazones with Togni's reagent under mild conditions was developed. Various functional groups including ester, methoxy, dimethoxy, nitro, halogen, and heterocyclic compounds were tolerated. This simple and green strategy provides a practical tool to construct C(sp3)-CF3 bonds.

A facile synthesis of isomeric C -(2,2,2-trifluoroethyl)anilines

Trofymchuk, Sergii,Bezdudny, Andrii V.,Pustovit, Yurii M.,Lukin, Oleg,Boyko, Alexander N.,Chekotylo, Alexey,Tolmachev, Andrei A.,Mykhailiuk, Pavel K.

experimental part, p. 1974 - 1976 (2012/08/27)

Three isomers of C-(2,2,2-trifluoroethyl)aniline were prepared on a multigram scale from readily available nitrophenylacetic acids in two steps. First, the carboxy groups of the latter were converted into the trifluoromethyl moieties by treatment with sul

The reactions of copper-dibromodifluoromethane-amide systems with alcohols

Clark, James H.,McClinton, Martin A.,Blade, Robert J.

, p. 257 - 267 (2007/10/02)

1,1,1-Trifluoro-2-arylethanes can be prepared by the trifluoromethyldehydroxylation of benzyl alcohols using the copper-dibromodifluoromethane-amide reaction system, although the yields are low.The mechanism of the reaction may involve chelation of the substrate to copper so that α-substituted benzyl alcohols and other alcohols are unreactive.

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