145919-18-2Relevant articles and documents
Enantiospecific Syntheses of α-(Fluoromethyl)tryptophan Analogues: Interactions with Tryptophan Hydroxylase and Aromatic L-Amino Acid Decarboxylase
Zembower, David E.,Gilbert, Judith A.,Ames, Matthew M.
, p. 305 - 313 (2007/10/02)
α-Fluoromethyl amino acids are enzyme-activated irreversible inhibitors of amino acid decarboxylases.Aromatic L-amino acid decarboxylase (AADC) is the enzyme responsible for the final step in the biosynthesis of both dopamine and serotonin via decarboxyla