1459764-59-0Relevant articles and documents
Diaminodiacid-based solid-phase synthesis of peptide disulfide bond mimics
Cui, Hong-Kui,Guo, Ye,He, Yao,Wang, Feng-Liang,Chang, Hao-Nan,Wang, Yu-Jia,Wu, Fang-Ming,Tian, Chang-Lin,Liu, Lei
, p. 9558 - 9562 (2013/09/23)
The antimicrobial peptide tachyplesin I was used as a model to apply the title strategy, which was developed for the preparation of peptidic macrocycles with double disulfide surrogates. The folding and activity of the tachyplesin I analogues were found to be sensitive to the structure of the disulfide surrogates, thus underlining the necessity of a flexible synthetic route for generating disulfide bond surrogates with high structural diversity. Copyright