14598-91-5

Upstream product

• 14717-97-6 2-Amino-3-(4-thiazolyl)-propanoic acid 
• 501-53-1 benzyl chloroformate 
• 127862-85-5 2-Benzyloxycarbonylamino-3-thiazol-4-yl-propionic acid 2,2,2-trifluoro-ethyl ester 
• 501-53-1 carbonochloridic acid benzyl ester 

Downstream Products

• 14598-92-6 2-benzyloxycarbonylamino-3-thiazol-4-yl-propionic acid 4-nitro-phenyl ester 
• 127862-85-5 2-Benzyloxycarbonylamino-3-thiazol-4-yl-propionic acid 2,2,2-trifluoro-ethyl ester 
• 14717-98-7 N-(2-benzyloxycarbonylamino-3-thiazol-4-yl-propionyl)-glycine benzyl ester 
• 14598-94-8 N-(2-benzyloxycarbonylamino-3-thiazol-4-yl-propionyl)-glycine 
• 14598-93-7 N'-(2-benzyloxycarbonylamino-3-thiazol-4-yl-propionyl)-hydrazinecarboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Resolution of non-proteinogenic amino acids via microbial lipase-catalyzed enantioselective transesterification

A number of non-proteinogenic amino acids bearing aliphatic side chains were resolved with moderate to good enantioselectivities (E = 15-42) through the Burkholderia cepacia lipase-catalyzed enantioselective transesterification of the 2,2,2-trifluoroethyl esters of their N-benzyloxycarbonyl derivatives with methanol as a nucleophile in diisopropyl ether.

Porcine Pancreatic Lipase Catalyzed Enantioselective Hydrolysis of Esters of N-Protected Unusual Amino Acids

Porcine pancreatic lipase catalyzed the highly enantioselective hydrolysis of a kind of α-substituted carboxylic esters, i.e., the 2,2,2-trifluoroethyl esters of the N-benzyloxycarbonyl derivatives of unusual amino acids.