14717-97-6

Basic information

• Product Name: DL-4-Thiazolylalanine
• Synonyms: (+/-)-alpha-Amino-4-thiazolepropanoic acid;4-Thiazolealanine;alpha-Amino-4-thiazolepropanoic acid;beta-(4-Thiazolyl)-DL-Alanine;DL-alpha-Amino-4-thiazolepropionic acid;3-(4-Thiazolyl)-DL-alanine;2-AMino-3-(thiazol-4-yl)propanoic acid;3-(4-Thiazolyl)alanine
• CAS NO: 14717-97-6
• Molecular Formula: C₆H₈N₂O₂S
• Molecular Weight: 172.20
• Mol File: 14717-97-6.mol
• Article Data: 2

Chemical Properties

• Melting Point: 237℃
• Boiling Point: 353.32 °C at 760 mmHg
• Flash Point: 167.482 °C
• Appearance: /
• Density: 1.433
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.616
• Storage Temp.: 2-8°C
• CAS DataBase Reference: DL-4-Thiazolylalanine(CAS DataBase Reference)
• NIST Chemistry Reference: DL-4-Thiazolylalanine(14717-97-6)
• EPA Substance Registry System: DL-4-Thiazolylalanine(14717-97-6)

Safety Data

• Hazardous Substances Data: 14717-97-6(Hazardous Substances Data)

Usage

General Description

DL-4-Thiazolylalanine is a chemical compound consisting of a thiazole ring and an alanine residue. It is a non-proteinogenic amino acid that has been used in biochemical and pharmaceutical research. The thiazole ring in DL-4-Thiazolylalanine is known for its ability to chelate metal ions, making it a versatile compound for various applications. DL-4-Thiazolylalanine has been studied for its potential as a therapeutic agent, particularly in the treatment of neurodegenerative diseases and cancer. Its unique structure and properties make DL-4-Thiazolylalanine an interesting target for further research and development.

InChI:InChI=1/C6H8N2O2S/c7-5(6(9)10)1-4-2-11-3-8-4/h2-3,5H,1,7H2,(H,9,10)

Upstream product

• 131116-54-6 diethyl (4-thiazolyl)methylacetamidomalonate 

Downstream Products

• 14598-91-5 2-Benzyloxycarbonylamino-3-thiazol-4-yl-propionic acid 
• 14717-98-7 N-(2-benzyloxycarbonylamino-3-thiazol-4-yl-propionyl)-glycine benzyl ester 
• 14598-93-7 N'-(2-benzyloxycarbonylamino-3-thiazol-4-yl-propionyl)-hydrazinecarboxylic acid tert-butyl ester 
• 14598-94-8 N-(2-benzyloxycarbonylamino-3-thiazol-4-yl-propionyl)-glycine 
• 14598-92-6 2-benzyloxycarbonylamino-3-thiazol-4-yl-propionic acid 4-nitro-phenyl ester 
• 108868-73-1 ((S)-1-{1-[(1S,2S)-1-Cyclohexylmethyl-2-hydroxy-4-(4-methyl-pentanoylamino)-butylcarbamoyl]-2-thiazol-4-yl-ethylcarbamoyl}-2-phenyl-ethyl)-carbamic acid tert-butyl ester 
• 108868-87-7 Boc-Phe-dl-(4-thiazolyl)alanine methyl ester 
• 108868-88-8 Boc-Phe-dl-(4-thiazolyl)alanine 
• 14598-91-5 2-benzyloxycarbonylamino-3-thiazol-4-yl-propionic acid 

Relevant articles and documents

Substituted quinoxaline-2-ones as glutamate receptor antagonists

A novel series of substituted quinoxaline 2-ones useful as neuroprotective agents are taught. Novel intermediates, processes of preparation, and pharmaceutical compositions containing the compounds are also taught. The compounds are glutamate receptor antagonists and are useful in the treatment of stroke, cerebral ischemia, or cerebral infarction resulting from thromboembolic or hemorrhagic stroke, cerebral vasospasms, hypoglycemia, cardiac arrest, status epilepticus, perinatal asphyxia, anoxia, seizure disorders, pain, Alzheimer's, Parkinson's, and Huntington's Diseases.