14599-72-5

Basic information

• Product Name: 1-(m-Methoxyphenyl)-2-imidazolidinone
• Synonyms: 1-(m-Methoxyphenyl)-2-imidazolidinone;1-(3-Methoxyphenyl)imidazolidin-2-one
• CAS NO: 14599-72-5
• Molecular Formula: C₁₀H₁₂N₂O₂
• Molecular Weight: 192.21
• Mol File: 14599-72-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Density: 1.197g/cm³
• Refractive Index: 1.561
• CAS DataBase Reference: 1-(m-Methoxyphenyl)-2-imidazolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(m-Methoxyphenyl)-2-imidazolidinone(14599-72-5)
• EPA Substance Registry System: 1-(m-Methoxyphenyl)-2-imidazolidinone(14599-72-5)

Safety Data

• Hazardous Substances Data: 14599-72-5(Hazardous Substances Data)

Usage

General Description

1-(m-Methoxyphenyl)-2-imidazolidinone is an organic compound with the chemical formula C11H13NO2. It is a derivative of imidazolidinone and contains a methoxy group attached to the meta position of a phenyl ring. 1-(m-Methoxyphenyl)-2-imidazolidinone has been used in various industries, including as a pharmaceutical intermediate and in the synthesis of other organic compounds. It has also been studied for its potential biological activities, such as antimicrobial and anti-inflammatory properties. Additionally, it has been investigated for its potential use in the development of new materials and as a chemical reagent in organic synthesis. Overall, 1-(m-Methoxyphenyl)-2-imidazolidinone has a range of industrial and biological applications due to its unique chemical structure and properties.

InChI:InChI=1/C10H12N2O2/c1-14-9-4-2-8(3-5-9)12-7-6-11-10(12)13/h2-5H,6-7H2,1H3,(H,11,13)

Upstream product

• 120-93-4 imidazolidone 
• 766-85-8 3-methoxy-1-iodobenzene 
• 536-90-3 m-Anisidine 
• 14088-85-8 N¹-(3-methoxyphenyl)ethane-1,2-diamine 
• 530-62-1 1,1'-carbonyldiimidazole 
• 18523-47-2 3-azidopropanoic acid 
• 110-70-3 N,N`-dimethylethylenediamine 

Downstream Products

• 92491-23-1 4,5-dihydro-1-(3-methoxyphenyl)-3-methylimidazol-2(1H)-one 
• 1225208-19-4 C₁₈H₂₇N₃O₂ 

Relevant articles and documents

PYRROLIDINE COMPOUNDS

The present invention provides compounds of the Formula (I) wherein L is selected from the group consisting of -CH2NHCH2-, -CH2NH-, -NH-, -S-, -S(O)-, -S(O)2-, -O-, -OCH2-, -OCH2CH2O-, -NHSO2NH-, (II) and (III), or a pharmaceutically acceptable salt thereof; a compound of the formula: (IV), processes for preparing the compounds and their salts, a pharmaceutical composition, and methods of treating patients in need of such treatment.

Mild, convenient and versatile Cu-mediated synthesis of N-aryl-2-imidazolidinones

A mild, general, convenient and practical methodology for the selective copper-mediated mono N-arylation of unprotected 2-imidazolidinone was developed. Strong electron-donating groups and free hydroxy and amino groups on the aryl iodide substrates were well tolerated. The use of n-butanol as the solvent for the copper-catalysed mono-arylation of 2-imidazolidinone is unprecedented.

Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds

The present invention relates to copper-catalyzed carbon-heteroatom and carbon-carbon bond-forming methods. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between the nitrogen atom of an amide or amine moiety and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. In additional embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between a nitrogen atom of an acyl hydrazine and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. In other embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between the nitrogen atom of a nitrogen-containing heteroaromatic, e.g., indole, pyrazole, and indazole, and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-oxygen bond between the oxygen atom of an alcohol and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. The present invention also relates to copper-catalyzed methods of forming a carbon-carbon bond between a reactant comprising a nucleophilic carbon atom, e.g., an enolate or malonate anion, and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. Importantly, all the methods of the present invention are relatively inexpensive to practice due to the low cost of the copper comprised by the catalysts.