146013-57-2Relevant academic research and scientific papers
3-Methylenetetrahydrofurans and 3-Methylenepyrrolidines by Addition of 2-(Bromozincmethyl)-2-alkenyl Ethers or 2-(Chloromagnesiomethyl)-2-alkenyl Ethers to Aldehydes, Ketones and Imines followed by Pd(0)-Catalyzed Cyclization
Louw, Jaap van der,Baan, Juul L. van der,Stichter, Henk,Out, Gerardus J. J.,Kanter, Franciscus J. J. de,et al.
, p. 9877 - 9900 (2007/10/02)
Reaction of 2-(bromozincmethyl)-2-alkenyl ethers 1 or 2-(chloromagnesiomethyl)-2-alkenyl ethers 2 with aldehydes, ketones and imines affords the addition products 4 and 8, which undergo Pd(0)-catalyzed cyclization to the 3-methylenetetrahydrofurans 6 (Rs
