1460293-46-2

Upstream product

• 1460293-45-1 (4S)-4-((1,3-dithian-2-yl)methyl)-2-(4-methoxyphenyl)-1,3-dioxane 
• 1460293-44-0 (4S)-4-(iodomethyl)-2-(4-methoxyphenyl)-1,3-dioxane 
• 103708-37-8 (2S,4S)-4-hydroxymethyl-2-(p-methoxymethyl)-1,3-dioxane 

Downstream Products

• 1460293-59-7 (10S,E)-11-(2-((S)-4-((tert-butyldimethylsilyl)oxy)-2-((4-methoxybenzyl)oxy)butyl)-1,3-dithian-2-yl)-11-hydroxy-10-methylundec-7-en-1-yl pivalate 
• 1460293-60-0 (10S,E)-11-(2-((S)-4-((tert-butyldimethylsilyl)oxy)-2-((4-methoxybenzyl)oxy)butyl)-1,3-dithian-2-yl)-11-hydroxy-10-methylundec-7-en-1-yl pivalate 
• 1460293-48-4 (10S,11R,14S,E)-16-((tert-butyldimethylsilyl)oxy)-11-hydroxy-14-((4-methoxybenzyl)oxy)-10-methyl-12-oxohexadec-7-en-1-yl pivalate 
• 1460293-49-5 (S,E)-10-((4R,5S)-5-((S)-4-((tert-butyldimethylsilyl)oxy)-2-((4-methoxybenzyl)oxy)butyl)-2,2-dimethyl-1,3-dioxolan-4-yl)undec-7-en-1-yl pivalate 
• 1460293-53-1 C₃₆H₆₄O₇Si 
• 1460293-51-9 6-((4S,5S)-5-((S)-2-((4R,5S)-5-((S)-4-((tert-butyldimethylsilyl)-oxy)-2-((4-methoxybenzyl)oxy)butyl)-2,2-dimethyl-1,3-dioxolan-4-yl)propyl)-2,2-dimethyl-1,3-dioxolan-4-yl)hexyl pivalate 
• 1460293-50-8 (7S,8S,10S)-10-((4R,5S)-5-((S)-4-((tert-butyldimethylsilyl)oxy)-2-((4-methoxybenzyl)oxy)butyl)-2,2-dimethyl-1,3-dioxolan-4-yl)-7,8-dihydroxyundecyl pivalate 

Relevant academic research and scientific papers

Diastereoselective synthesis of the C14-C29 fragment of amphidinol 3

An efficient stereoselective synthesis of the C14-C29 fragment highlighting a coupling reaction between a 1,3-dithiane derivative and an α-branched aldehyde was realized. This highly convergent synthesis involved two chiral pools, l-malic acid and (+)-camphorsulfonic acid, which are the starting compounds to control the six stereogenic centers present in the C14-C29 fragment of amphidinol 3.