146039-01-2Relevant academic research and scientific papers
Investigation of Stereoselectivities in the Coupling Reactions of 1-O-Methyl-3,5-di-O-p-toluoyl-2-deoxyribofuranoside with Purines and Pyrimidines
Janardhanam, Selvasekaran,Nambiar, Krishnan P.
, p. 3657 - 3660 (2007/10/02)
Stereoselectivities in the coupling rection between 1-O-methyl-3,5-di-O-p-toluoyl-2-deoxyribofuranoside and suitably protected purine and pyrimidine derivatives have been examined in acetonitrile with varying equivalents of SnCl4.The best result in α-nucleoside formation was obtained when the coupling reaction was carried out in the presence of ten equivalents of SnCl4.
