14606-16-7

Basic information

• Product Name: 1,3,4-Oxadiazol-2(3H)-one, 3-(4-bromophenyl)-5-methyl-
• CAS NO: 14606-16-7
• Molecular Formula: C9H7BrN2O2
• Molecular Weight: 255.071
• Mol File: 14606-16-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,3,4-Oxadiazol-2(3H)-one, 3-(4-bromophenyl)-5-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,4-Oxadiazol-2(3H)-one, 3-(4-bromophenyl)-5-methyl-(14606-16-7)
• EPA Substance Registry System: 1,3,4-Oxadiazol-2(3H)-one, 3-(4-bromophenyl)-5-methyl-(14606-16-7)

Safety Data

• Hazardous Substances Data: 14606-16-7(Hazardous Substances Data)

Upstream product

• 54624-59-8 4-bromo-3-(4-bromo-phenyl)-sydnone 
• 75-36-5 acetyl chloride 
• 26537-61-1 3-(4-bromophenyl)sydnone 
• 108-24-7 acetic anhydride 
• 6415-68-5 N-nitroso-N-phenylglycine 

Downstream Products

• 1449770-54-0 2-(4-bromophenyl)-5-methyl-4-(1H-tetrazol-1-yl)-2H-1,2,4-triazol-3(4H)-one 
• 1001077-42-4 4-(2-hydroxyethyl)-5-methyl-2-(4-bromophenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 666751-06-0 4-amino-2-(4-bromophenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 

Relevant articles and documents

The reaction of sydnones with bromine in acetic anhydride revisited: A new route to 5-substituted-3-aryl-1,3,4-oxadiazol-2(3H)-ones from N-aryl-N-bromocarbonylhydrazines

The reaction of 3-phenylsydnone with bromine in acetic anhydride to form 5-methyl-3-phenyl-1,3,4-oxadiazol-2(3H)-one has been reexamined and improved. A new mechanism involving a bromocarbonylhydrazine species is proposed and its intermediacy is supported

Transformation of the sydnone ring into oxadiazolinones. A convenient one-pot synthesis of 3-aryl-5-methyl-1,3,4-oxadiazolin-2-ones from 3- arylsydnones and their antimicrobial activity

3-Arylsydnones (Ia-u) have been converted into the corresponding 3-aryl- 5-methyl-1,3,4-oxadiazolin-2-ones (IIIa-u) by a single-step reaction with bromine in acetic anhydride. In the preliminary screening of all these compounds, the halogen-substituted de