146142-35-0Relevant academic research and scientific papers
Synthesis and biological activity of enantiomeric oxapenemcarboxylic acids
Pfaendler,Neumann,Bartsch
, p. 1179 - 1184 (1992)
The synthesis of enantiomerically pure potassium (5R)- and (5S)-trans-2-tert-butyl-6-hydroxymethyloxapenem-3-carboxylates is reported. Surprisingly, both enantiomers were active antibiotics and β-lactamase inhibitors.
