Synthesis p. 1179 - 1184 (1992)
Update date:2022-08-04
Topics:
Pfaendler
Neumann
Bartsch
The synthesis of enantiomerically pure potassium (5R)- and (5S)-trans-2-tert-butyl-6-hydroxymethyloxapenem-3-carboxylates is reported. Surprisingly, both enantiomers were active antibiotics and β-lactamase inhibitors.
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Doi:10.1021/acs.organomet.9b00659
(2020)Doi:10.1002/jhet.1744
(2014)Doi:10.1016/0040-4020(68)89019-2
(1968)Doi:10.1016/S0960-894X(00)00627-2
(2001)Doi:10.1080/00397919809458710
(1998)Doi:10.1021/ja01104a038
(1953)
