1462367-22-1

Basic information

• Product Name: methyl 2-{[(4-methoxyphenyl)methyl]amino}butanoate
• Synonyms: methyl 2-{[(4-methoxyphenyl)methyl]amino}butanoate
• CAS NO: 1462367-22-1
• Molecular Weight: 237.299
• Mol File: 1462367-22-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 2-{[(4-methoxyphenyl)methyl]amino}butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-{[(4-methoxyphenyl)methyl]amino}butanoate(1462367-22-1)
• EPA Substance Registry System: methyl 2-{[(4-methoxyphenyl)methyl]amino}butanoate(1462367-22-1)

Safety Data

• Hazardous Substances Data: 1462367-22-1(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 7682-18-0 methyl 2-aminobutanoate hydrochloride 

Downstream Products

• 1462367-31-2 5-ethyl-1-[(4-methoxyphenyl)methyl]-3-methyl-5-phenylimidazolidine-2,4-dione 
• 1462367-26-5 2-{[(4-methoxyphenyl)methyl][methyl(phenyl)carbamoyl]amino}butanoic acid 

Relevant articles and documents

Palladium Catalyzed C-Arylation of Amino Acid Derived Hydantoins

Palladium(II) trifluoroacetate (5 mol %) catalyzes the C-arylation of N,N-disubstituted hydantoins by aryl iodides in good yield. The reaction proceeds through base-promoted enolization of the amino acid derived hydantoins, and the resulting 5,5-disubstituted hydantoins may be deprotected at one or both N atoms to yield biologically active structures or alternatively hydrolyzed to the parent α-aryl α-amino acids. The reaction is successful with a variety of parent amino acids and a range of electron-rich and electron-poor aryl iodides.