146253-27-2

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 146253-26-1 4-(phenylsulfonyl)-1,3-dimethyl-2,4-dihydropyrrolo<3,4-b>indole 
• 98-09-9 benzenesulfonyl chloride 
• 146253-23-8 1-(phenylsulfonyl)-2-ethyl-3-indolyl methyl ketone 
• 17422-23-0 1-(2-ethyl-1H-indol-3-yl)-ethan-1-one 
• 146253-25-0 1-(phenylsulfonyl)-2-(1-azidoethyl)-3-indolyl methyl ketone 
• 146253-24-9 1-(phenylsulfonyl)-2-(1-bromoethyl)-3-indolyl methyl ketone 

Relevant academic research and scientific papers

Total Syntheses of Ellipticine Alkaloids and their Amino Analogues

Staudinger reaction of 9 with triphenylphosphine gave 2,4-dihydropyrroloindole 10.Treatment of 10 with di-tert-butyl dicarbonate and 4-dimethylaminopyridine gave 11.Diels-Alder reaction of 11 with 3,4-pyridyne gave cycloadducts 12 and 13, which were converted into ellipticine 1 and isoellipticine 2.New amino analogues of ellipticine 27 and 28 were also synthesized by this new route.Key words: Ellipticine, 2,4-Dihydropyrroloindole, Staudinger Reaction