146253-75-0Relevant articles and documents
Inhibition of the Tetracycline Efflux Antiport Protein by 13-Thio-Substituted 5-Hydroxy-6-deoxytetracyclines
Nelson, Mark L.,Park, Britt H.,Andrews, Janey S.,Georgian, Vlasios A.,Thomas, Richard C.,Levy, Stuart B.
, p. 370 - 377 (1993)
A series of 13-(alkylthio) and 13-(arylthio) derivatives of 5-hydroxy-6-deoxytetracycline (tetracycline, Tc) were synthesized and compared to the clinically used antibiotics tetracycline, methacycline, and minocycline for their ability to inhibit tetracyc