
Journal of Medicinal Chemistry p. 370 - 377 (1993)
Update date:2022-09-26
Topics:
Nelson, Mark L.
Park, Britt H.
Andrews, Janey S.
Georgian, Vlasios A.
Thomas, Richard C.
Levy, Stuart B.
A series of 13-(alkylthio) and 13-(arylthio) derivatives of 5-hydroxy-6-deoxytetracycline (tetracycline, Tc) were synthesized and compared to the clinically used antibiotics tetracycline, methacycline, and minocycline for their ability to inhibit tetracyc
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