14627-78-2Relevant academic research and scientific papers
The Enantioselective Synthesis of an Important Intermediate to the Antiviral, (-)-Carbovir
Handa, Sheetal,Earlam, George J.,Geary, Phillip J.,Hawes, John E.,Phillips, Gareth T.,et al.
, p. 1885 - 1886 (2007/10/02)
Two new routes to the important intermediate (-)-8 for the carbocyclic-based nucleosides are reported.The intermediate (-)-8 has also been synthesised in high enantiomeric excess via an enzymatic resolution of the racemic amide (+)-8 or an enzymatic enantiotopic hydrolysis of the meso diester 12.
The Photochemical Reaction of Benzene with Ethylenes: Studies with Allyl Compounds, Enamines, Vinyl Sulphide, and 5,6-Dichlorobicyclohept-2-ene
Gilbert, Andrew,Samsudin, M. Wahid bin,Taylor, Grahame N.,Wilson, Steve
, p. 1225 - 1229 (2007/10/02)
Benzene undergoes regio- and stereo-selective meta photocycloaddition to methyl but-3-enoate and pent-1-en-4-ol but methyl allyl ketone and NN-dimethylallylamine yield only products of the addend: likewise irradiation of benzene with enamines or methyl vinyl sulphide at 254 nm does not yield photoadducts.The meta photocycloadducts of benzene with methyl but-3-enoate and vinyl acetate and the ketones obtained by oxidation of the adducts from pent-1-en-4-ol are all essentially photostable and do not undergo Norrish Type II eliminations.The dechlorination products of the meta photocycloaddition of 5,6-trans-dichlorobocyclohept-2-ene and benzene undergo a retro-Diels-Alder addition at high temperatures, but the C8H8 isomer formed is cyclo-octatetraene.
