146303-72-2Relevant academic research and scientific papers
PRODUCTION, PROPERTIES, AND MASS-SPECTROMETRIC INVESTIGATION OF THE DABSYLATES OF PHENOLS
Dem'yanov, P. I.,Khimenes, M. P.,Bogdashkina, V. I.,Petrosyan, V. S.
, p. 767 - 777 (2007/10/02)
The reaction of monohydric and dihydric phenols and phloroglucinol with 4'-(dimethylamino)azobenzene-4-sulfonyl chloride (dabsyl chloride) leads to the respective mono-, di-, and triabsylates of the phenols.Their structures were confirmed by IR, PMR, and mass spectrometry.A scheme is proposed for the dissociation of the phenol dabsylates under electron impact.The transformation of the phenols into the derivatives by reaction with dabsyl chloride is recommended for highly sensitive and selective determination of the individual phenols by high-performance liquid chromat ography with spectrophotometric detection and for spectrophotometric determination of total phenol content.
Determination of phenols as their dabsylates by high-performance liquid chromatography
Dem'yanov, P. I.,Khimenes, M. P.,Petrosyan, V. S.
, p. 1489 - 1493 (2007/10/02)
We show that the monohydric and the dihydric phenols, and also the trihydric phloroglucinol, easily react with 4'-(dimethylamino)azobenzene-4-sulphonyl chloride (dabsyl chloride) to give stable mono-, di-, and tridabsylates respectively, which are strongly light-absorbing in the visible region of the spectrum.It is established that the phenol dabsylates can be separated by normal- and by reverse-phase high-performance liquid chromatography; the limit of detection of monohydric phenol dabsylates with liquid chromatography is 1-2 ng, or a few picomoles.
