1463045-73-9Relevant academic research and scientific papers
Acid-catalyzed reactions of 3-hydroxy-2-oxindoles with electron-rich substrates: Synthesis of 2-oxindoles with all-carbon quaternary center
Kinthada, Lakshmana K.,Ghosh, Santanu,De, Subhadip,Bhunia, Subhajit,Dey, Dhananjay,Bisai, Alakesh
, p. 6984 - 6993 (2013/10/08)
A Lewis acid catalyzed reaction of in situ generated 2H-indol-2-one (9) with various 2π and other electron-rich substrates has been developed. A variety of electron-rich substrates such as allyl/methallyltrimethylsilane, phenylacetylene, styrenes, acetophenone, and indoles have been used. The methodology provides a straightforward approach for the synthesis of 2-oxindoles with an all-carbon quaternary center at the pseudobenzylic position.
