146309-04-8

Basic information

• Product Name: 6-Oxa-7-azabicyclo[3.2.2]non-8-ene-7-carboxylic acid, phenylmethyl ester
• CAS NO: 146309-04-8
• Molecular Formula: C15H17NO3
• Molecular Weight: 259.305
• Mol File: 146309-04-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 387.2±32.0 °C(Predicted)
• Density: 1.209±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 6-Oxa-7-azabicyclo[3.2.2]non-8-ene-7-carboxylic acid, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Oxa-7-azabicyclo[3.2.2]non-8-ene-7-carboxylic acid, phenylmethyl ester(146309-04-8)
• EPA Substance Registry System: 6-Oxa-7-azabicyclo[3.2.2]non-8-ene-7-carboxylic acid, phenylmethyl ester(146309-04-8)

Safety Data

• Hazardous Substances Data: 146309-04-8(Hazardous Substances Data)

Upstream product

• 3426-71-9 Benzyl N-hydroxycarbamate 
• 876938-53-3 Cyclohepta-1,3-diene 

Downstream Products

• 113340-08-2 cis-1-(amino)-4-acetoxycyclohept-2-ene 
• 113340-07-1 trans-1-(amino)-4-chlorocyclohept-2-ene 
• 113340-15-1 1-(amino)cyclohepta-2,4-diene 
• 280-05-7 8-azabicyclo[3.2.1]octane 
• 182128-39-8 4-<(benzyloxycarbonyl)amino>cyclohept-2-enone 
• 95798-92-8 cis-4-(<(benzyloxy)carbonyl>amino)cycloheptanol 
• 142010-00-2 4-<(benzyloxycarbonyl)amino>cycloheptanone 
• 146309-01-5 trop-6-ene 
• 529-17-9 tropane 
• 159022-56-7 benzyl 8-oxa-9-azabicyclo<3.2.2>nonane-9-carboxylate 
• 113340-14-0 cis-4-[(benzyloxycarbonyl)amino]cyclohept-2-enol 

Relevant articles and documents

Synthetic Approaches to Nortropanes and Nortrop-6-enes; Intramolecular Displacement by Nitrogen in 7-Membered Rings

The synthesis of simple nortropane and nortrop-6-ene derivatives from cyclohepta-1,3-diene is described.The key intermediates are trans-1-amino-4-chloro-cycloheptanes and -cyclohept-2-enes which are derived efficiently from the corresponding cis-amino-alcohols and undergo intramolecular cyclisation.Corresponding derivatisation of cyclohexa- and cycloocta-1,3-dienes is explored and attempts to achieve Pd-catalysed cyclisation of 1-amino-4-acetoxy-derivatives is described.Nitrogen inversion data for selected nortropane derivatives are included. Key Words: nortropanes/enes; 1,4-disubstitute cyclohexanes, cycloheptanes, cyclooctanes and -enes; intramolecular cyclisation; slow nitrogen inversion.