146335-67-3

Upstream product

• 962-39-0 L-Phenylalanine benzyl ester 
• 79463-77-7 N-cyanodiphenylcarbonimidate 
• 962-39-0 DL-phenylalanine benzyl ester 

Downstream Products

• 146335-77-5 3-amino-7-benzyl-1,2,4,6-tetrabicyclo<3.3.0>octan-8-one 
• 146335-86-6 2-(5-Amino-2-methyl-2H-[1,2,4]triazol-3-ylamino)-3-phenyl-propionic acid benzyl ester 
• 146335-88-8 2-(5-Amino-1-methyl-1H-[1,2,4]triazol-3-ylamino)-3-phenyl-propionic acid benzyl ester 

Relevant academic research and scientific papers

Preparation of Imidazolones from N-cyano-N'-methylcarboxyguanidines. An Unusual C-N-Bond Formation in the Hydrogenolysis of a Benzyl Ester in an Attempted Synthesis of an Inhibitor of Carboxypeptidase A

Hydrogenolysis of the benzyl ester 5 gave the imidazolone 6 rather than the desired acid 1, and the related benzyl ester 11 also hydrogenolysed to the imidazolone 12.Examination of the hydrolysis of simpler guanidine derivatives with trifluoroacetic acid

Synthesis of 1,2,4-Triazoles and 1,2,4,6-Tetraazabicyclo[3.3.0]octanes from diphenyl cyanocarbonimidate. Competition between addition of hydrazines to esters or nitriles

The reaction of hydrazine with suitably substituted isoureas gives tetraazabicyclo[3.3.0]octanes. The products obtained in this reaction are extremely susceptible to the nature of the substrate and the reaction conditions, but a suitable combination of th