Preparation of Imidazolones from N-cyano-N'-methylcarboxyguanidines. An Unusual C-N-Bond Formation in the Hydrogenolysis of a Benzyl Ester in an Attempted Synthesis of an Inhibitor of Carboxypeptidase A

DOI: 10.1016/S0040-4020(01)80431-2

Source and publish data:

Tetrahedron p. 6885 - 6898 (1993)

Update date:2022-07-29

Topics:

Authors:

Garratt, Peter J.

Thorn, Simon N.

Wrigglesworth, Roger

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)80431-2

Hydrogenolysis of the benzyl ester 5 gave the imidazolone 6 rather than the desired acid 1, and the related benzyl ester 11 also hydrogenolysed to the imidazolone 12.Examination of the hydrolysis of simpler guanidine derivatives with trifluoroacetic acid

Full text of DOI:10.1016/S0040-4020(01)80431-2

Products guided by the article

Product name:N-cyano-N'-(S)-(1-benzyloxycarbonyl-2-phenylethyl)-O-phenylisourea

Cas No:146335-67-3

R&D Labs maybe for 146335-67-3

RongCheng K&S Chemical Co.,Ltd

Contact:0631-7336369

Address:rongcheng ,shandong province china
Joyochem Co., Ltd.

website:https://sdjingyuan.lookchem.com/

Contact:86-531-82687998

Address:Factory Building 11, Jinan Comprehensive free trade zone, Shandong, China
Nanjing Fubang Chemical Co.,Ltd

Contact:+86-25-83179199

Address:5F,Tianzheng international plaza,No399 Zhongyang Road ,Nanjing China
Shanghai Mio Chemical Co., Ltd

Contact:0086 21- 64401188-622

Address:16 Floor NO.2 Jiefang Building, No. 4855 Dushi Road, 201100 Shanghai, P.R.China
zonk drug r&d limited

Contact:+86-20-32051076

Address:1105,Building A, International Business Incubator,Science City

Relevant to this article

INVESTIGATION OF THE ALKYLATION OF NITROAZOLES WITH α-HALOKETONES BY 13C, 15N, AND 14N NMR

Doi:10.1007/BF00961497
(1990)
Doi:10.1021/ja01233a024
(1944)
Sequential three-component reactions: Synthesis, regioselectivity and application of functionalized dihydropyridines (DHPs) for the creation of fused naphthyridines

Doi:10.1016/j.tetlet.2011.04.098
(2011)
Tandem ring opening/cyclization of vinylcyclopropanes: A facile synthesis of chiral bicyclic amidines

Doi:10.1002/anie.201100375
(2011)
Asymmetric epoxidation of α,β-unsaturated ketones via an amine-thiourea dual activation catalysis

Doi:10.1016/j.tetlet.2021.152941
(2021)
Copper(II) and Nickel(II) Complexes of N,N',N'',N'''-Tetrakis(2-aminoethyl)-1,4,7,11-tetra-azacyclotetradecane (taei), -1,4,8,12-tetra-azacyclopentadecane (taep), and -1,5,9,13-tetra-azacyclohexadecane (taeh). Crystal Structures of 4, and 4, and ....

Doi:10.1039/DT9900002763
(1990)

Article Doi