Preparation of Imidazolones from N-cyano-N'-methylcarboxyguanidines. An Unusual C-N-Bond Formation in the Hydrogenolysis of a Benzyl Ester in an Attempted Synthesis of an Inhibitor of Carboxypeptidase A

DOI: 10.1016/S0040-4020(01)80431-2

Source and publish data:

Tetrahedron p. 6885 - 6898 (1993)

Update date:2022-07-29

Topics:

Authors:

Garratt, Peter J.

Thorn, Simon N.

Wrigglesworth, Roger

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)80431-2

Hydrogenolysis of the benzyl ester 5 gave the imidazolone 6 rather than the desired acid 1, and the related benzyl ester 11 also hydrogenolysed to the imidazolone 12.Examination of the hydrolysis of simpler guanidine derivatives with trifluoroacetic acid

Full text of DOI:10.1016/S0040-4020(01)80431-2

Products guided by the article

Product name:N-cyano-N'-(S)-(1-benzyloxycarbonyl-2-phenylethyl)-O-phenylisourea

Cas No:146335-67-3

R&D Labs maybe for 146335-67-3

Shijiazhuang Sdyano Fine Chemical Co., Ltd

Contact:+86-311-89830448

Address:NO.48 Ta Nan Road,Yuhua District,Shijiazhuang,Hebei,China
Hangzhou Ocean Chemical Co., Ltd.

website:http://www.hzoceanchem.com

Contact:+86-571-88025872, 28272092, 28272096

Address:Room 623 ,Building No 1 , COFCO Radius Commercial Center Xiwen Road, Xiacheng District, Hangzhou, Zhejiang Province, China
Hangzhou Eastbiopharm Co.,Ltd.

Contact:+86-571-88931780

Address:Hangzhou,China
HangZhou HuaYe Chemical Technology Co.,Ltd

Contact:+86-13505815007

Address:hangzhou
Shanghai Zhihua ChemTech Co., Ltd.

Contact:+86-13774313779

Address:Room 817 Suite B 3333 Shenjiang Road

Relevant to this article

INVESTIGATION OF THE ALKYLATION OF NITROAZOLES WITH α-HALOKETONES BY 13C, 15N, AND 14N NMR

Doi:10.1007/BF00961497
(1990)
Doi:10.1021/ja01233a024
(1944)
Sequential three-component reactions: Synthesis, regioselectivity and application of functionalized dihydropyridines (DHPs) for the creation of fused naphthyridines

Doi:10.1016/j.tetlet.2011.04.098
(2011)
Tandem ring opening/cyclization of vinylcyclopropanes: A facile synthesis of chiral bicyclic amidines

Doi:10.1002/anie.201100375
(2011)
Asymmetric epoxidation of α,β-unsaturated ketones via an amine-thiourea dual activation catalysis

Doi:10.1016/j.tetlet.2021.152941
(2021)
Copper(II) and Nickel(II) Complexes of N,N',N'',N'''-Tetrakis(2-aminoethyl)-1,4,7,11-tetra-azacyclotetradecane (taei), -1,4,8,12-tetra-azacyclopentadecane (taep), and -1,5,9,13-tetra-azacyclohexadecane (taeh). Crystal Structures of 4, and 4, and ....

Doi:10.1039/DT9900002763
(1990)

Article Doi