146426-36-0

Basic information

• Product Name: antibiotic APHE 2
• Synonyms: antibiotic APHE 2
• CAS NO: 146426-36-0
• Molecular Formula: C14H14N2O
• Molecular Weight: 226.27376
• Mol File: 146426-36-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 390.4°Cat760mmHg
• Flash Point: 189.9°C
• Appearance: /
• Density: 1.24g/cm³
• Vapor Pressure: 2.66E-06mmHg at 25°C
• Refractive Index: 1.658
• CAS DataBase Reference: antibiotic APHE 2(CAS DataBase Reference)
• NIST Chemistry Reference: antibiotic APHE 2(146426-36-0)
• EPA Substance Registry System: antibiotic APHE 2(146426-36-0)

Safety Data

• Hazardous Substances Data: 146426-36-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H14N2O/c1-2-5-11-9-15-16-13(11)8-10-6-3-4-7-12(10)14(16)17/h3-4,6-9,15H,2,5H2,1H3

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Relevant articles and documents

Identification and isolation of insecticidal oxazoles from Pseudomonas spp.

Two new and five known oxazoles were identified from two different Pseudomonas strains in addition to the known pyrones pseudopyronine A and B. Labeling experiments confirmed their structures and gave initial evidence for a novel biosynthesis pathway of t

A 5 - (3 - indolyl) - oxazole compound of preparation method

The invention discloses a preparation method of a 5-(3-indolyl)-oxazole compound with a structure as shown in the formula (I). The method comprises the following step: in the presence of iodine and dimethyl sulfoxide, a compound with a structure as shown in the formula (II) and a compound with a structure as shown in the formula (III) undergo a contact reaction. Raw materials used in the preparation method are cheap and easily available. The preparation method is simple and the preparation step is short. In addition, the contact reaction can be carried out by a one kettle way during synthetic operation. Yield is high and can reach 84%. The preparation method provided by the invention is especially suitable for industrial production.

One-pot total synthesis: The first total synthesis of chiral alkaloid pimprinol A and the facile construction of its natural congeners from amino acids

In this work, we accomplished the first total synthesis of chiral alkaloid pimprinol A and the facile construction of its natural congeners: pimprinine, pimprinethine, pimprinaphine, WS-30581A, WS-30581B, laboradorin 1, uguenenazole, balsoxine, texamine in one-pot from commercially available starting materials including amino acids. Further investigating into the mechanism revealed that this improved transformation was achieved by the integration of iodination, Kornblum oxidation, condensation, decarboxylation, annulation, and oxidation reaction sequence.