146426-54-2

Basic information

• Product Name: 3-azido-1,2,3-trideoxy-1-(3,4-dihydro-5-Methyl-2,4-dioxo-1(2H)-pyriMidinyl)-D-erythro-Pentofuranuronic acid
• Synonyms: 3-azido-1,2,3-trideoxy-1-(3,4-dihydro-5-Methyl-2,4-dioxo-1(2H)-pyriMidinyl)-D-erythro-Pentofuranuronic acid
• CAS NO: 146426-54-2
• Molecular Formula: C₁₀H₁₁N₅O₅
• Mol File: 146426-54-2.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-azido-1,2,3-trideoxy-1-(3,4-dihydro-5-Methyl-2,4-dioxo-1(2H)-pyriMidinyl)-D-erythro-Pentofuranuronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-azido-1,2,3-trideoxy-1-(3,4-dihydro-5-Methyl-2,4-dioxo-1(2H)-pyriMidinyl)-D-erythro-Pentofuranuronic acid(146426-54-2)
• EPA Substance Registry System: 3-azido-1,2,3-trideoxy-1-(3,4-dihydro-5-Methyl-2,4-dioxo-1(2H)-pyriMidinyl)-D-erythro-Pentofuranuronic acid(146426-54-2)

Safety Data

• Hazardous Substances Data: 146426-54-2(Hazardous Substances Data)

Upstream product

• 30516-87-1 3'-azido-2',3'-deoxythymidine 

Downstream Products

• 209255-42-5 C₅₂H₅₀N₅O₁₀P 
• 948916-06-1 C₂₅H₃₅N₁₉O₉ 
• 948916-05-0 C₂₄H₃₃N₁₉O₉ 

Relevant articles and documents

Chimeric (α-amino acid + nucleoside-β-amino acid)n peptide oligomers show sequence specific DNA/RNA recognition

An α/β-peptide backbone oligonucleotide comprising natural α-amino acids alternating with a β-amino acid component derived from thymidine sequence specifically recognizes and binds to deoxy- and ribo-oligoadenylates in triplex mode. The Royal Society of Chemistry.

Ruthenium tetraoxide catalyzed oxidation of nucleosides: A facile synthesis of 5'-carboxylic acid derivatives

Purine and pyrimidine nucleosides have been oxidized to the corresponding 5'-carboxylic acids using potassium persulfate and ruthenium trichloride under basic conditions. The method provides easy access to nucleosides bearing 3'-amino and 5'-carboxylic acid functionalities from 3'-azido compounds as exemplified by oxidation of AZT followed by reduction of the acid.

Novel helical foldamers: Organized heterogeneous backbone folding in 1:1 α/nucleoside-derived-β-amino acid sequences

Secondary structural conformation of hybrid oligo-peptides comprised of 1:1 alternating Nucleoside Derived β-Amino acid (NDA) and l-amino acid residues has been reported. The studies reveal that the NDA residues organize the heterogeneous backbone featuri