146451-24-3Relevant academic research and scientific papers
E- OR Z-SELECTIVE WITTIG REACTIONS IN THE SYNTHESIS OF THE CARBACYCLIN ILOPROST
Westermann, Juergen,Harre, Michael,Nickisch, Klaus
, p. 8055 - 8056 (1992)
Wittig reaction of ketones 3 with 4-carboxybutyltriphenyl-phosphonium bromide generates the exocyclic 5,6 double bond of iloprost (1) in E/Z ratios between 35:65 and 90:10 depending on substituents and reaction conditions.
